Nuclear metabolism for the win! We are excited to publish two back-to-back manuscripts about nuclear metabolism. While the stories diverge into distinct concepts, it's exciting to see metabolic enzymes do so much in the nucleus. Read the original publication about MTHFD2 at Nature Communications.Nuclear localization of...
Savvas defended his PhD thesis in studies of Proteins and their isoforms ...
Congratulations Alisa, Remi and Uldana for successfully completing your Masters with flying colours! Alisa, Remi and Dana joined us in early 2024 to pursue their Masters internship. Alisa joined us from the Medical University of Vienna, pursuing her Masters in Molecular Precision Medicine; Remi joined us...
In an exciting new strategy, Savvas hypothetized that antibody enrichment would enrich modified (PTMs) and mutated bait peptides. Using MSFragger Open Search (Nesvilab) coupled to SAINTexpress, we identify differentially present peptidoforms.By re-analyzing the publicly available #HRAS WT vs. G12D interactomes, we specifically identify the positive...
After 4 years of constant hardwork and continuous perseverance, with 2 cool projects, Rito graduates his PhD in Biomedical Cancer Research with an Excellent Cum Laude from CRG/UPF. Congratulations to Dr. Ritobrata Ghose on the successful defense of his PhD! This significant achievement reflects his...
Our lab at the Centre for Genomic Regulation together with collaborators from the Vall d’Hebron Institute of Oncology has made an important discovery that could lead to new treatments for triple-negative breast cancer. This aggressive form of breast cancer lacks the receptors targeted by current...
It's hard to believe it's already been 4 years since Natalia first stepped into the Sdelci Lab as a bright-eyed and eager PhD student. We remember her first day like it was yesterday – she was so excited to dive into her cancer metabolism research...
Matilda graduated in Biology at the Ludwig-Maximilian University in Munich, Germany in 2020 and specialized in Neuro- and Behavioral Sciences with a Master's degree at the Universität Leipzig, Germany in 2022. During the Master's, she joined the Immunometabolism and Inflammation lab at the Centro de...
Congratulations Sara Musa Afaneh for successfully completing your Masters in Molecular Biology, Biochemistry and Biomedicine from UAB!Sara joined us as a Masters student from the Autonomous University of Barcelona (UAB) to study epigenetic modifications in breast cancer. Now that she is a Masters graduate, we...
A new study co-led by Savvas Kourtis from our lab and Amandine Moretton from Joanna Loizou's lab at the CeMM, Vienna reveals that in response to DNA damage, such as from chemotherapy drugs, the nucleus of a cell activates antioxidant enzymes to protect itself. We...
